70 analyte PFAS test method highlights need for expanded testing of PFAS in drinking water

n this community-led pilot study we sought to investigate the utility of expanded per- and polyfluoroalkyl substances (PFAS) testing for drinking water, using a targeted analysis for 70 PFAS and the Total Oxidizable Precursor (TOP) Assay which can indicate the presence of precursor PFAS. PFAS were detected in 30 out of 44 drinking water samples across 16 states; 15 samples would exceed US EPA’s proposed maximum contaminant levels for six PFAS. Twenty-six unique PFAS were identified, including 12 not covered by either US EPA Methods 537.1 or 533. An ultrashort chain PFAS, PFPrA, had the highest frequency of detection, occurring in 24 of 30 samples. It was also the PFAS reported at the highest concentration in 15 of these samples. We created a data filter to model how these samples would be reported under the upcoming fifth Unregulated Contaminant Monitoring Rule (UCMR5) requirements. All of the 30 samples with PFAS quantified by the 70 PFAS test had one or more PFAS present that would not be captured if the UCMR5 reporting requirements were followed. Our analysis suggests the upcoming UCMR5 will likely underreport PFAS in drinking water, due to limited coverage and higher minimum reporting limits. Results were inconclusive on the utility of the TOP Assay for monitoring drinking water. The results from this study provide important information to community participants regarding their current PFAS drinking water exposure. In addition, these results suggest gaps that need to be addressed by regulatory and scientific communities, in particular, the need for expanded targeted analysis of PFAS, the development of a sensitive, broad spectrum PFAS test, and further investigation into ultrashort chain PFAS.